Description

Vasopressin, ((2-Mercapto)Propionic Acid)(1)-(Lys-N(6)-Biotin)(8)- CAS NO 130154-83-5 is a chemically modified, biotinylated analog of the neurohypophysial hormone vasopressin, designed for advanced research and diagnostic applications. This derivative is engineered to provide a high-affinity handle for streptavidin/avidin-based detection, purification, and immobilization systems, significantly enhancing experimental versatility and signal amplification. It is primarily utilized by researchers in pharmaceutical development, biochemistry, and molecular biology for studying vasopressin receptor interactions, signal transduction pathways, and developing novel bioanalytical assays.

Application

• Biochemical Research: As a high-specificity probe for studying vasopressin V1a and V2 receptor binding, activation, and internalization mechanisms.
• Diagnostic Assay Development: Serving as a critical component in the development of sensitive ELISA, Western blot, or other immunoassay formats for vasopressin detection.
• Affinity Purification: Immobilization onto streptavidin-coated resins for the selective capture and purification of vasopressin receptors or interacting proteins from complex biological samples.
• Cellular Imaging: Conjugation with fluorescent streptavidin complexes for the visualization and localization of vasopressin receptors in live or fixed cells via microscopy.
• Drug Discovery: Use in high-throughput screening (HTS) platforms to identify and characterize novel agonists or antagonists targeting the vasopressin receptor family.
• Proteomics & Protein Interaction Studies: Employed in pull-down experiments and mass spectrometry to map vasopressin receptor interactomes and signaling complexes.

Basic Information

Product Name	Vasopressin, ((2-Mercapto)Propionic Acid)(1)-(Lys-N(6)-Biotin)(8)- CAS NO 130154-83-5
CAS No.	130154-83-5
Molecular Formula	C58H89N17O15S2
Molecular Weight	1304.6 g/mol
Synonyms	[1-(2-Mercaptopropionic acid), 8-Lysine(biotinamide)]-Vasopressin; Biotinylated Vasopressin; Biotin-Vasopressin; Biotin-Arg8-Vasopressin; AVP-Biotin; [Lys8(Biotin), Mpa1]-Vasopressin; Biotin-Lys-Vasopressin; Vasopressin Biotin Conjugate
EINECS	Contact for details

Quality Control

Our Vasopressin, ((2-Mercapto)Propionic Acid)(1)-(Lys-N(6)-Biotin)(8)- is manufactured under strict quality-controlled conditions suitable for research use. Each batch undergoes comprehensive analytical characterization including HPLC for purity assessment, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing purity, peptide content, and analytical data are available upon request to ensure traceability and meet your specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content (AAA)	≥ 80%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.