Description

3-(2-Chloroethyl)-6,7,8,9-Tetrahydro-7-Methoxy-2-Methyl-4H-Pyrido[1,2-A]Pyrimidin-4-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular research. Pharmaceutical manufacturers and advanced R&D laboratories need this material for developing next-generation therapeutic agents, where consistent quality and reliable supply are paramount.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex drug molecules targeting specific biological pathways.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold for research into new therapeutic compounds, especially in neurology and cardiology.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic & Institutional Research: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Process Chemistry & Scale-Up: Employed in developing and optimizing robust, scalable synthetic routes from laboratory to pilot plant scale.
• Reference Standard: High-purity grades can be utilized as analytical standards for quality control and method validation in API production.

Basic Information

Product Name	3-(2-Chloroethyl)-6,7,8,9-Tetrahydro-7-Methoxy-2-Methyl-4H-Pyrido[1,2-A]Pyrimidin-4-One
CAS No.	130049-80-8
Molecular Formula	C13H17ClN2O2
Molecular Weight	268.74 g/mol
Synonyms	7-Methoxy-2-methyl-3-(2-chloroethyl)-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one; 3-(2-Chloroethyl)-7-methoxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one; 130049-80-8; Pyrido[1,2-a]pyrimidin-4-one, 3-(2-chloroethyl)-6,7,8,9-tetrahydro-7-methoxy-2-methyl-; A key intermediate for certain kinase inhibitors.
EINECS	Contact for details

Quality Control

Our 3-(2-Chloroethyl)-6,7,8,9-Tetrahydro-7-Methoxy-2-Methyl-4H-Pyrido[1,2-A]Pyrimidin-4-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with full traceability are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.