Description

4-Fluoro-2-(Trifluoromethyl)Phenol is a versatile fluorinated phenolic compound, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents, imparts valuable properties such as enhanced lipophilicity and metabolic stability to target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms contribute to improved biological activity and environmental profile.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs).
• Polymer Modification: Acts as a monomer or additive to introduce fluorine into polymer chains, enhancing chemical resistance, thermal stability, and surface properties.
• Organic Electronics: Building block for electron-transport materials, semiconductors, and other components in OLEDs and organic photovoltaic cells.
• Chemical Research & Development: A valuable reagent for exploring new reaction pathways and creating novel fluorinated compounds in academic and industrial R&D labs.

Basic Information

Product Name	4-Fluoro-2-(Trifluoromethyl)Phenol
CAS No.	130047-19-7
Molecular Formula	C7H4F4O
Molecular Weight	180.10 g/mol
Synonyms	2-(Trifluoromethyl)-4-fluorophenol; 4-Fluoro-α,α,α-trifluoro-o-cresol; 4-Fluoro-2-trifluoromethylphenol; 2-Trifluoromethyl-4-fluorophenol; 4-Fluoro-α,α,α-trifluoro-2-methylphenol; Phenol, 4-fluoro-2-(trifluoromethyl)-; 4-Fluoro-2-(trifluoromethyl)benzenol
EINECS	Contact for details

Quality Control

Our 4-Fluoro-2-(Trifluoromethyl)Phenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistent quality that meets the stringent requirements of advanced synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents and bases. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.