Description

2-Chloro-5-Methyl-3H-Pyrrolo[3,2-D]Pyrimidin-4(5H)-One is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents, particularly in kinase inhibitor research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of targeted small molecule drugs, especially protein kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides and fungicides that leverage its unique pyrrolopyrimidine core.
• Chemical Biology: Employed as a molecular scaffold or probe in the study of enzyme function and biological pathways.
• Material Science Precursor: Potential starting material for the synthesis of organic electronic materials or ligands for metal-organic frameworks (MOFs).
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis and library production.

Basic Information

Product Name	2-Chloro-5-Methyl-3H-Pyrrolo[3,2-D]Pyrimidin-4(5H)-One
CAS No.	129872-84-0
Molecular Formula	C7H6ClN3O
Molecular Weight	183.59 g/mol
Synonyms	2-Chloro-5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-one; 2-Chloro-5-methyl-7H-pyrrolo[3,2-d]pyrimidin-4-ol; 4(5H)-Pyrrolo[3,2-d]pyrimidinone, 2-chloro-5-methyl-; 2-Chloro-5-methyl-4-hydroxy-7H-pyrrolo[3,2-d]pyrimidine; 129872-84-0; 2-Chloro-5-methyl-4-pyrrolo[3,2-d]pyrimidinone
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Methyl-3H-Pyrrolo[3,2-D]Pyrimidin-4(5H)-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry for identity confirmation. Certificates of Analysis (COA) are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.