Description

5-Benzyl-2,4-Dichloro-5H-Pyrrolo[3,2-D]Pyrimidine is a high-value heterocyclic organic compound belonging to the pyrrolopyrimidine class, serving as a critical building block in advanced chemical synthesis. Its primary commercial value lies in its role as a versatile pharmaceutical intermediate for the development of novel active pharmaceutical ingredients (APIs), particularly kinase inhibitors. This compound is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors seeking to develop new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted kinase inhibitors and other small-molecule drugs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Chemical Biology: Serves as a core scaffold for designing chemical probes and tool compounds in drug discovery.
• Material Science: Potential building block for advanced organic electronic materials and ligands in catalysis.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	5-Benzyl-2,4-Dichloro-5H-Pyrrolo[3,2-D]Pyrimidine
CAS No.	129872-83-9
Molecular Formula	C₁₃H₉Cl₂N₃
Molecular Weight	278.14 g/mol
Synonyms	5-Benzyl-2,4-dichloro-5H-pyrrolo[3,2-d]pyrimidine; 2,4-Dichloro-5-benzyl-5H-pyrrolo[3,2-d]pyrimidine; Pyrrolo[3,2-d]pyrimidine, 5-benzyl-2,4-dichloro-5H-; 129872-83-9; 5H-Pyrrolo[3,2-d]pyrimidine, 5-benzyl-2,4-dichloro-; 5-Benzyl-2,4-dichloro-7-azaindole (common name reference)
EINECS	Contact for details

Quality Control

Our 5-Benzyl-2,4-Dichloro-5H-Pyrrolo[3,2-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.