Description

4-Amino-3-S-Glutathionylphenol is a specialized biochemical compound that functions as a glutathione conjugate of an aminophenol derivative. This product is significant for its role as a key intermediate in the study of metabolic pathways, oxidative stress, and detoxification mechanisms. It is primarily needed by research institutions and pharmaceutical developers focused on biochemistry, toxicology, and the development of novel therapeutic or diagnostic agents.

Application

• Biochemical Research: Used as a critical reference standard and intermediate in studies of glutathione metabolism and conjugation reactions.
• Toxicology Studies: Employed to investigate the metabolic fate and detoxification pathways of phenolic compounds and related xenobiotics.
• Pharmaceutical Development: Serves as a building block or metabolite analog in the research and development of new drugs targeting oxidative stress.
• Analytical Standard: Utilized as a high-purity standard for calibration in HPLC, LC-MS, and other analytical methods for metabolite identification and quantification.
• Enzymology Research: Applied in studies involving glutathione S-transferase (GST) enzymes to understand substrate specificity and catalytic activity.

Basic Information

Product Name	4-Amino-3-S-Glutathionylphenol
CAS No.	129762-74-9
Molecular Formula	C16H23N4O7S
Molecular Weight	415.44 g/mol
Synonyms	4-Amino-3-(glutathion-S-yl)phenol; 3-(Glutathion-S-yl)-4-aminophenol; 4-AP-GSH; Glutathione conjugate of 4-aminophenol; γ-Glu-Cys-Gly conjugate of 4-amino-3-hydroxyphenyl; L-γ-Glutamyl-L-cysteinylglycine S-(4-amino-3-hydroxyphenyl) ester; 4-Aminophenol glutathione adduct
EINECS	Contact for details

Quality Control

Our 4-Amino-3-S-Glutathionylphenol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.