Description

Cecropin A (1-8)-Melittin (1-18) Amide H-Lys-Trp-Lys-Leu-Phe-Lys-Lys-Ile-Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Nh2 is a potent synthetic hybrid antimicrobial peptide (AMP) designed to combine the broad-spectrum activity of cecropin with the membrane-lytic properties of melittin. This engineered peptide is of significant interest for its enhanced stability and reduced hemolytic activity compared to its parent peptides, making it a valuable tool for advanced biomedical research and therapeutic development. It is primarily utilized by researchers and developers in pharmaceutical discovery, microbiology, and biotechnology for studying novel antibiotic mechanisms and developing next-generation anti-infective agents.

Application

• Antimicrobial Mechanism Research: Fundamental studies on peptide-membrane interactions, pore formation, and bacterial cell lysis.
• Pharmaceutical Lead Compound: Screening and development of novel antibiotic candidates with activity against drug-resistant bacteria.
• Biomaterial Coating: Development of antimicrobial surfaces for medical devices, implants, and wound dressings.
• Veterinary Medicine: Investigation of therapeutic applications for bacterial infections in animals.
• Cosmeceutical Research: Exploration of preservative or anti-acne properties in advanced skincare formulations.
• Academic & Institutional Research: A key reagent for laboratories focusing on immunology, peptide chemistry, and infectious diseases.

Basic Information

Product Name	Cecropin A (1-8)-Melittin (1-18) Amide H-Lys-Trp-Lys-Leu-Phe-Lys-Lys-Ile-Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Nh2
CAS No.	129696-23-7
Molecular Formula	C149H260N44O37
Molecular Weight	3195.0 g/mol (theoretical)
Synonyms	CA(1-8)M(1-18); Hybrid Peptide CA-M; Cecropin-Melittin Hybrid; Antimicrobial Hybrid Peptide; CAM; CA(1–8)M(1–18) amide; [Lys1, Trp2, Lys3, Leu4, Phe5, Lys6, Lys7, Ile8]-Cecropin A-(1-8)-[Gly1, Ile2, Gly3, Ala4, Val5, Leu6, Lys7, Val8, Leu9, Thr10, Thr11, Gly12, Leu13, Pro14, Ala15, Leu16, Ile17, Ser18]-Melittin amide
EINECS	Contact for details

Quality Control

Our Cecropin-Melittin hybrid peptide is manufactured under controlled conditions to ensure the highest standards of purity and biological activity. Each batch undergoes rigorous analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and endotoxin testing. Certificates of Analysis (COA) detailing all specifications and test results are available upon request to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Endotoxin	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.