Description

H-Val-Phe-Nh2 Hcl is a high-purity dipeptide derivative, specifically the hydrochloride salt of the H-Val-Phe-NH2 peptide. This compound serves as a critical building block (amino acid derivative) and pharmacological intermediate in advanced research and synthesis. It is primarily utilized by pharmaceutical R&D teams, peptide synthesis specialists, and biochemical research institutions for developing novel therapeutic agents and conducting structure-activity relationship studies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of more complex peptide-based drugs and bioactive molecules.
• Peptide Synthesis Building Block: Used in solid-phase and solution-phase peptide synthesis (SPPS) to construct specific peptide sequences.
• Biochemical Research: Employed in enzymatic studies, substrate specificity assays, and as a reference standard in analytical method development.
• Protease/Enzyme Inhibitor Development: Acts as a substrate analog or inhibitor scaffold in the research of enzymes like dipeptidyl peptidase IV (DPP-4).
• Chemical Biology Tool: Incorporated into probes or ligands for studying protein-protein interactions and cellular signaling pathways.
• Reference Standard: Serves as a high-purity standard for quality control and analytical testing (HPLC, MS) in peptide manufacturing.

Basic Information

Product Name	H-Val-Phe-Nh2 Hcl
CAS No.	129678-27-9
Molecular Formula	C14H22N3O3 • HCl
Molecular Weight	317.80 g/mol (for free base C14H22N3O3)
Synonyms	L-Valyl-L-phenylalaninamide hydrochloride; Val-Phe-NH2 • HCl; H-Val-Phe-NH2 hydrochloride; VF-NH2 hydrochloride; N-(N-L-Valyl-L-phenylalanyl)amide hydrochloride; Dipeptide VF-amide HCl; (S)-2-((S)-2-Amino-3-methylbutanamido)-3-phenylpropanamide hydrochloride
EINECS	Contact for details

Quality Control

Our H-Val-Phe-Nh2 Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral purity verification, and identity confirmation (IR, MS) to ensure it meets exacting research and pharmaceutical-grade standards. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (by chiral HPLC)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.