Description

5-Methoxymethyl-2-Deoxycytidine is a modified nucleoside derivative, a key building block in oligonucleotide synthesis and medicinal chemistry research. This compound matters for its role in creating structurally diverse nucleic acid analogs, enabling the development of novel therapeutics and research tools. It is primarily needed by pharmaceutical R&D teams, biotechnology companies, and academic laboratories focused on antisense oligonucleotides, siRNA, and other advanced nucleic acid-based modalities.

Application

• Oligonucleotide Synthesis: Serves as a critical phosphoramidite precursor for the solid-phase synthesis of modified DNA and RNA strands.
• Antisense & siRNA Therapeutics: Used to incorporate specific modifications that enhance stability, target affinity, and pharmacokinetic properties of therapeutic oligonucleotides.
• Medicinal Chemistry Research: Acts as a versatile scaffold for the discovery and optimization of nucleoside-based drug candidates.
• Biochemical Probes: Employed in the development of labeled nucleotides and probes for diagnostic assays and genomic research.
• Academic & Institutional Research: Fundamental material for studies in chemical biology, enzymology, and nucleic acid structure-function relationships.

Basic Information

Product Name	5-Methoxymethyl-2-Deoxycytidine
CAS No.	129580-10-5
Molecular Formula	C11H17N3O5
Molecular Weight	271.27 g/mol
Synonyms	5-(Methoxymethyl)-2'-deoxycytidine; 2'-Deoxy-5-(methoxymethyl)cytidine; 5-MMdC; dC(5-MM); 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(methoxymethyl)pyrimidine-2,4(1H,3H)-dione
EINECS	Contact for details

Quality Control

Our 5-Methoxymethyl-2-Deoxycytidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. Certificates of Analysis (COA) with full analytical data are provided to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.