Description

2-Pyrimidinecarboxylic Acid, 1,4,5,6-Tetrahydro- (9Ci) is a heterocyclic carboxylic acid derivative that serves as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its partially saturated pyrimidine core makes it a critical building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, antiviral agents, and enzyme inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that require a functionalized pyrimidine scaffold.
• Ligand Synthesis: Serves as a starting material for creating chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Peptidomimetics: Incorporated into peptide analogs to enhance metabolic stability and bioavailability in drug design.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic chemistry and scaffold diversification.
• Material Science: Potential monomer or additive for creating specialized polymers with unique electronic or thermal properties.

Basic Information

Product Name	2-Pyrimidinecarboxylic Acid, 1,4,5,6-Tetrahydro- (9Ci)
CAS No.	129578-99-0
Molecular Formula	C5H8N2O2
Molecular Weight	128.13 g/mol
Synonyms	1,4,5,6-Tetrahydro-2-pyrimidinecarboxylic acid; 1,4,5,6-Tetrahydropyrimidine-2-carboxylic acid; 2-Carboxy-1,4,5,6-tetrahydropyrimidine; Hexahydropyrimidine-2-carboxylic acid; Tetrahydro-2-pyrimidinecarboxylic acid; NSC 406173; AI3-52511
EINECS	Contact for details

Quality Control

Our 2-Pyrimidinecarboxylic Acid, 1,4,5,6-Tetrahydro- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.