Description

Tachyplesin Iii is a potent antimicrobial peptide (AMP) originally isolated from hemocytes of the horseshoe crab. This compound, with CAS number 129557-13-7, is valued for its broad-spectrum activity against bacteria, fungi, and certain viruses, coupled with a unique mechanism of action that disrupts microbial membranes. It is primarily utilized by researchers in pharmaceutical development, biotechnology, and life sciences for studying novel antibiotic pathways and developing new therapeutic agents.

Application

• Antimicrobial Research: Serves as a key reference standard and active compound in studies targeting multidrug-resistant (MDR) bacteria and fungi.
• Drug Discovery & Development: Used as a lead compound or template for designing novel peptide-based antibiotics and therapeutic agents.
• Biochemical & Mechanistic Studies: Employed to investigate membrane disruption mechanisms, peptide-lipid interactions, and host defense peptide biology.
• Veterinary & Aquaculture Applications: Explored for potential use in animal health products and as an alternative to conventional antibiotics in aquaculture.
• Cosmeceutical & Preservative Research: Evaluated for its potential in topical formulations and as a natural preservative agent due to its antimicrobial properties.
• Diagnostic Reagent Development: Used in the development of assays and kits for detecting specific microbial targets or studying immune responses.

Basic Information

Product Name	Tachyplesin Iii
CAS No.	129557-13-7
Molecular Formula	C95H139N31O26
Molecular Weight	2267.3 g/mol
Synonyms	Tachyplesin-3; Tachyplesin III; Tachyplesin-3 (Tachypleus tridentatus); Antimicrobial peptide Tachyplesin III; Tachyplesin Iii (CAS 129557-13-7); Tachyplesin III peptide; Tachyplesin-3, horseshoe crab; 17-residue cationic antimicrobial peptide
EINECS	Contact for details

Quality Control

Our Tachyplesin Iii is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for critical research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity determination and Mass Spectrometry (MS) for identity confirmation. Certificates of Analysis (COA) detailing all quality parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing desiccated under an inert atmosphere. Allow the vial to warm to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%
Biological Activity	Assayed (Contact for details)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.