Description

Antithrombin Rouen Iv is a specific variant of the serine protease inhibitor antithrombin, a critical regulatory protein in the blood coagulation cascade. This high-purity biological compound is essential for research and development in the fields of hematology, thrombosis, and hemostasis. It is primarily utilized by pharmaceutical researchers, diagnostic kit manufacturers, and academic institutions studying coagulation disorders and developing novel anticoagulant therapies.

Application

• Biochemical Research: Used as a key reference standard and reagent in studies of blood coagulation pathways, enzyme kinetics, and inhibitor mechanisms.
• Diagnostic Development: Serves as a critical component in the calibration and validation of diagnostic assays for antithrombin deficiency and related thrombophilic conditions.
• Pharmaceutical R&D: Employed in the screening and development of new anticoagulant and antithrombotic drug candidates.
• Quality Control: Acts as a purity standard for the production and quality assurance of therapeutic antithrombin concentrates.
• Clinical Studies: Utilized in research investigating the role of specific antithrombin mutations (like the Rouen variant) in disease pathology.

Basic Information

Product Name	Antithrombin Rouen Iv
CAS No.	129553-81-7
Molecular Formula	Contact for details
Molecular Weight	~58 kDa (Approximate, glycosylated protein)
Synonyms	Antithrombin III Rouen; ATIII Rouen; Serpin C1 Rouen variant; Antithrombin Rouen; AT Rouen; Antithrombin 4 (Rouen); Antithrombin Deficiency Rouen Type; AT III Variant Rouen
EINECS	Contact for details

Quality Control

Our Antithrombin Rouen Iv is produced and handled under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, activity, and identity. We adhere to relevant quality guidelines suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Consistent with Antithrombin
Purity (HPLC)	≥ 95%
Biological Activity (Chromogenic Assay)	≥ 90% of stated activity
Endotoxin	< 1.0 EU/mg
Moisture (Karl Fischer)	< 3.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.