Description

Galanin Message Associated Peptide (16-41) Amide is a synthetic peptide fragment corresponding to the C-terminal region of the Galanin Message-Associated Peptide (GMAP). This compound is a crucial research tool for investigating the complex physiological roles of galanin and its associated peptides in the central and peripheral nervous systems. It is primarily utilized by researchers and developers in the fields of neuroscience, endocrinology, and pharmaceutical discovery to study receptor interactions, signal transduction pathways, and potential therapeutic applications.

Application

• Neuroscientific Research: Used as a reference standard and active agent in studies exploring the role of galaninergic systems in pain modulation, feeding behavior, cognition, and stress responses.
• Receptor Binding Assays: Employed in competitive binding studies to characterize galanin receptor subtypes (GalR1, GalR2, GalR3) and their affinity profiles.
• Signal Transduction Studies: Applied in cellular models to investigate downstream effects of GMAP receptor activation on intracellular signaling cascades.
• Antibody Production & Immunoassays: Serves as an antigen for generating specific antibodies used in ELISA, Western blotting, and immunohistochemistry techniques.
• Pharmaceutical R&D: Acts as a lead compound or tool for the development and screening of novel peptide-based therapeutics targeting neurological and metabolic disorders.
• Biochemical Standardization: Used as a purified standard in analytical method development (e.g., HPLC, MS) for quantifying GMAP-related peptides in biological samples.

Basic Information

Product Name	Galanin Message Associated Peptide (16-41) Amide
CAS No.	129541-35-1
Molecular Formula	C124H202N40O34
Molecular Weight	2797.2 g/mol (theoretical)
Synonyms	GMAP (16-41) amide; Galanin-Message Associated Peptide (16-41) amide; Galanin message-associated peptide fragment 16-41 amide; Porcine Galanin Message-Associated Peptide (16-41) amide; pGMAP (16-41) amide; GMAP-16-41-NH2; H-Gly-Trp-Ala-Thr-Leu-Asn-Ser-Ala-Gly-Gln-His-Leu-Ala-Ser-Asn-Gln-Arg-Gly-Tyr-Leu-Ala-Pro-Ala-Glu-Asp-Glu-Asn-Pro-His-Tyr-Ile-Pro-Ala-Gly-Leu-Ala-Pro-Arg-Asn-NH2
EINECS	Contact for details

Quality Control

Our Galanin Message Associated Peptide (16-41) Amide is manufactured under strict quality systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. We provide full traceability and support research integrity with detailed Certificates of Analysis (COA) containing data from HPLC, MS, and amino acid analysis. Our quality commitment aligns with the standards expected for high-purity biochemical reagents.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption. For long-term storage, keep under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	± 10% of theoretical composition
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.