Description

Hymenistatin I CAS NO 129536-23-8 is a bioactive cyclic peptide compound of significant interest in advanced biochemical research. This compound matters for its role as a potent immunosuppressive agent, making it a valuable tool for studying cellular signaling pathways and immune response modulation. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on immunology, oncology, and novel therapeutic discovery.

Application

• Immunosuppressive Research: A key reference standard for studying the inhibition of T-cell activation and cytokine production.
• Drug Discovery & Development: Used as a lead compound or pharmacological probe in the search for new anti-inflammatory and autoimmune disease therapies.
• Mechanistic Studies: Employed to investigate specific intracellular targets and signal transduction pathways involved in immune regulation.
• Biochemical Assay Development: Serves as a critical control or standard in high-throughput screening (HTS) assays for immunomodulatory activity.
• Academic Research: Utilized in university and institutional labs for fundamental research in immunopharmacology and medicinal chemistry.
• Preclinical Studies: Applied in animal models to evaluate efficacy and mechanism of action for potential therapeutic candidates.

Basic Information

Product Name	Hymenistatin I
CAS No.	129536-23-8
Molecular Formula	C₄₃H₆₈N₁₀O₁₀
Molecular Weight	885.1 g/mol
Synonyms	Hymenistatin 1; Cyclo[-(N-Me-Ala)-(Leu)-(N-Me-Val)-(Pro)-(Phe)-(Pro)-(Phe)-(Pro)-]; [MeAla¹,MeVal³]-Cyclo(-Ala-Leu-Val-Pro-Phe-Pro-Phe-Pro-); Hymenistatin I Cyclic Peptide; NSC 339624; L-Mevalyl-L-prolyl-L-phenylalanyl-L-prolyl-L-phenylalanyl-L-prolyl-N-methyl-L-alanyl-L-leucyl- (cyclic peptide)
EINECS	Contact for details

Quality Control

Our Hymenistatin I is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing including HPLC for purity, MS for identity confirmation, and NMR for structural verification. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. Due to its hygroscopic (moisture-sensitive) nature, the container should be allowed to reach room temperature before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.