Description

Pth (64-84) (Human) is a synthetic peptide fragment corresponding to residues 64-84 of the human parathyroid hormone. This high-purity peptide is a critical research tool for studying calcium homeostasis, bone metabolism, and endocrine signaling pathways. It is essential for researchers and developers in the fields of pharmaceutical R&D, metabolic disease studies, and biochemical assay development who require reliable, well-characterized bioactive peptides.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of parathyroid hormone (PTH) receptor binding, signal transduction, and biological activity.
• Assay Development: Serves as a critical component in the development and validation of immunoassays (ELISA, RIA) for PTH detection and quantification.
• Drug Discovery: Employed in high-throughput screening (HTS) platforms to identify and characterize novel PTH receptor agonists or antagonists for therapeutic applications.
• Structure-Activity Relationship (SAR) Studies: Provides a defined peptide sequence for investigating the functional domains of human PTH and designing peptide analogs.
• Quality Control: Acts as a system suitability standard in the quality control of related pharmaceutical products and diagnostic kits.
• Academic Research: Utilized in university and institutional labs for fundamental research into bone biology, renal function, and disorders like hyperparathyroidism and osteoporosis.

Basic Information

Product Name	Pth (64-84) (Human)
CAS No.	129449-07-6
Molecular Formula	C115H185N35O34
Molecular Weight	2582.9 g/mol
Synonyms	Human Parathyroid Hormone (64-84); PTH (64-84); hPTH (64-84); Parathyroid Hormone Fragment (64-84); H-Asp-Leu-Gly-Lys-Gln-Asp-Ala-Asn-Val-Asp-Val-Leu-Trp-Lys-Leu-Leu-Gln-Asp-His-Val-OH; PTH (Human 64-84); Parathyrin (64-84)
EINECS	Contact for details

Quality Control

Every batch of Pth (64-84) (Human) is manufactured and analyzed under strict quality management systems. Our products undergo rigorous quality testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis, to ensure compliance with research-grade standards. Comprehensive Certificates of Analysis (COA) detailing purity, peptide content, and analytical data are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store the lyophilized powder desiccated at -20°C. Reconstituted solutions should be aliquoted and stored at -80°C to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by amino acid analysis)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.