Description

Pyro-Glutamyl-Glutamyl-Glycyl-Seryl-Aspartic Acid is a high-purity synthetic peptide sequence of significant interest in advanced biochemical research and development. This compound serves as a critical building block and model substrate for studying enzymatic processes, protein-protein interactions, and signal transduction pathways. It is primarily utilized by pharmaceutical R&D teams, biotechnology firms, and academic institutions focused on peptide therapeutics, diagnostic assay development, and proteomics.

Application

• Pharmaceutical Research & Development: As a key intermediate or reference standard in the discovery and optimization of novel peptide-based drugs and biologics.
• Biochemical Assay Development: Used as a specific substrate or inhibitor in enzymatic activity assays to study protease and peptidase kinetics.
• Proteomics and Cell Signaling Studies: Employed as a tool compound to investigate cleavage sites, post-translational modifications, and cellular signaling cascades.
• Diagnostic Reagent Formulation: Incorporated into high-sensitivity diagnostic kits and reagents for detecting specific antibodies or biomarkers.
• Cosmeceutical Ingredient Research: Investigated for potential bioactive properties in advanced skincare and dermatological formulations.
• Academic & Institutional Research: Serves as a purified standard for method validation, chromatography calibration, and fundamental biochemical studies.

Basic Information

Product Name	Pyro-Glutamyl-Glutamyl-Glycyl-Seryl-Aspartic Acid
CAS No.	129276-56-8
Molecular Formula	C20H28N6O12
Molecular Weight	544.47 g/mol
Synonyms	pGlu-Glu-Gly-Ser-Asp-OH; Pyroglutamylglutamylglycylserylaspartic acid; L-Pyroglutamyl-L-glutamylglycyl-L-seryl-L-aspartic acid; 5-Oxo-L-prolyl-L-α-glutamylglycyl-L-seryl-L-aspartic acid; pGlu-Glu-Gly-Ser-Asp; (2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(5S)-5-oxopyrrolidine-2-carbonyl]amino]-4-carboxybutanoyl]amino]acetyl]amino]-3-hydroxypropanoyl]amino]butanedioic acid; pE-E-G-S-D
EINECS	Contact for details

Quality Control

Our Pyro-Glutamyl-Glutamyl-Glycyl-Seryl-Aspartic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and stringent controls for residual solvents and related substances. We provide full traceability and Certificates of Analysis (COA) are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed in a dry environment to prevent moisture uptake. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.