Description

N,n-Bis[(1,1-Dimethylethoxy)Carbonyl]-5-Oxo-, 1,1-Dimethylethyl Ester (Wxg02486) is a high-purity, protected amino acid derivative used as a critical building block in advanced organic synthesis. This compound is valued for its role in facilitating complex peptide coupling and protecting group strategies, ensuring high yields and selectivity in sensitive reactions. It is an essential intermediate for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing novel therapeutic peptides and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to introduce specific, protected amino acid sequences.
• Protecting Group Chemistry: Serves as a reagent featuring tert-butoxycarbonyl (Boc) protecting groups, crucial for multi-step synthetic routes.
• Bioconjugation: Employed in the development of peptide-drug conjugates and other bioconjugated molecules for targeted therapies.
• Academic & Industrial R&D: A valuable tool for research chemists in universities and corporate labs exploring new synthetic methodologies.
• Custom Synthesis: Used by fine chemical manufacturers for the contract production of specialized, non-commercial intermediates.

Basic Information

Product Name	N,n-Bis[(1,1-Dimethylethoxy)Carbonyl]-5-Oxo-, 1,1-Dimethylethyl Ester (Wxg02486)
CAS No.	129241-89-0
Molecular Formula	C19H33NO7
Molecular Weight	387.47 g/mol
Synonyms	tert-Butyl N,N-bis(tert-butoxycarbonyl)-5-oxo-L-norvalinate; L-Norvaline, 5-oxo-, N,N-bis[(1,1-dimethylethoxy)carbonyl]-, 1,1-dimethylethyl ester; Boc-L-Glu(OtBu)-OtBu; N,N-Bis-Boc-L-glutamic acid 1-tert-butyl ester; 5-Oxo-L-norvaline derivative; Protected L-glutamic acid derivative; WXG02486; Amino acid protecting reagent
EINECS	Contact for details

Quality Control

Every batch of N,n-Bis[(1,1-Dimethylethoxy)Carbonyl]-5-Oxo-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure compliance with exacting industry standards for fine chemical intermediates. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.5%
Optical Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.