Description

1,3-Dihydro-7-Bromo-5-(2-Chlorophenyl)-1,3-Dimethyl-2H-1,4-Benzodiazep In-2-One is a high-purity, specialized benzodiazepine derivative of significant interest in advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate for the research and development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of complex, high-value molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel benzodiazepine-based therapeutic agents.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Chemical Synthesis: Employed in organic synthesis for introducing the 7-bromo-5-(2-chlorophenyl)-1,3-dimethyl-1,4-benzodiazepin-2-one scaffold into more complex molecular architectures.
• Preclinical Studies: Utilized in the development and testing of new chemical entities (NCEs) in biological assays.

Basic Information

Product Name	1,3-Dihydro-7-Bromo-5-(2-Chlorophenyl)-1,3-Dimethyl-2H-1,4-Benzodiazep In-2-One
CAS No.	129178-92-3
Molecular Formula	C17H14BrClN2O
Molecular Weight	377.66 g/mol
Synonyms	7-Bromo-5-(2-chlorophenyl)-1,3-dihydro-1,3-dimethyl-2H-1,4-benzodiazepin-2-one; 7-Bromo-5-(o-chlorophenyl)-1,3-dimethyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 7-Bromodiazepam; 7-Br-Diazepam; 7-Bromo-1,3-dihydro-1,3-dimethyl-5-(2-chlorophenyl)-2H-1,4-benzodiazepin-2-one; 7-Bromo-5-(2-chlorophenyl)-1,3-dimethyl-1H-1,4-benzodiazepin-2(3H)-one; 129178-92-3
EINECS	Contact for details

Quality Control

Our 1,3-Dihydro-7-Bromo-5-(2-Chlorophenyl)-1,3-Dimethyl-2H-1,4-Benzodiazep In-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.