Description

2-Chloro-7-Nitro-3H-Quinazolin-4-One is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is a critical intermediate in the development of novel pharmaceutical agents, particularly in kinase inhibitor research and other targeted therapies. It is primarily sought after by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of tyrosine kinase inhibitors and other small-molecule drug candidates.
• Agrochemical Research: Used in the development of new herbicides and fungicides with specific modes of action.
• Chemical Biology: Serves as a versatile scaffold for creating molecular probes and tool compounds to study biological pathways.
• Material Science: Investigated as a building block for advanced organic electronic materials and liquid crystals.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and novel heterocyclic chemistry.

Basic Information

Item	Details
Product Name	2-Chloro-7-Nitro-3H-Quinazolin-4-One
CAS No.	129112-64-7
Molecular Formula	C8H4ClN3O3
Molecular Weight	225.59 g/mol
Synonyms	2-Chloro-7-nitro-4(3H)-quinazolinone; 7-Nitro-2-chloro-3H-quinazolin-4-one; 4(3H)-Quinazolinone, 2-chloro-7-nitro-; 2-Chloro-7-nitroquinazolin-4(3H)-one; 129112-64-7; Quinazolinone derivative; 2-Cl-7-NO2-Quinazolin-4-one
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-7-Nitro-3H-Quinazolin-4-One is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.