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L-Lysine, N6-[(1,1-Dimethylethoxy)Carbonyl]-N2-[(Phenylmethoxy)Carbonyl]-, Phenylmethyl Ester CAS NO 128972-27-0


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CAS No.:128972-27-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

L-Lysine, N6-[(1,1-Dimethylethoxy)Carbonyl]-N2-[(Phenylmethoxy)Carbonyl]-, Phenylmethyl Ester is a protected derivative of the essential amino acid L-Lysine, specifically designed for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise control over amino acid side-chain reactivity during complex multi-step organic syntheses. It is primarily utilized in pharmaceutical R&D for the production of novel peptide-based therapeutics, diagnostic agents, and biochemical probes.

Application

  • Solid-Phase Peptide Synthesis (SPPS): Serves as a key building block with orthogonal protecting groups (Boc and Cbz) for the controlled elongation of peptide chains.
  • Pharmaceutical Intermediates: Used in the research and development of peptide hormones, enzyme inhibitors, and other bioactive peptide molecules.
  • Bioconjugation Chemistry: Facilitates the site-specific labeling or modification of peptides and proteins for diagnostic or therapeutic purposes.
  • Combinatorial Chemistry Libraries: A valuable reagent for generating diverse libraries of peptide compounds for high-throughput screening in drug discovery.
  • Academic & Industrial Research: Employed in laboratories focused on organic synthesis, medicinal chemistry, and chemical biology studies.

Basic Information

Product Name L-Lysine, N6-[(1,1-Dimethylethoxy)Carbonyl]-N2-[(Phenylmethoxy)Carbonyl]-, Phenylmethyl Ester
CAS No. 128972-27-0
Molecular Formula C26H34N2O6
Molecular Weight 470.56 g/mol
Synonyms Nα-Cbz-Nε-Boc-L-Lysine Benzyl Ester; Nα-Carbobenzoxy-Nε-tert-butoxycarbonyl-L-lysine Benzyl Ester; Z-Lys(Boc)-OBzl; Boc-Lys(Z)-OBzl; (S)-Benzyl 2-(((benzyloxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)hexanoate; N2-[(Benzyloxy)carbonyl]-N6-[(tert-butoxycarbonyl)]-L-lysine Benzyl Ester; Cbz-Lys(Boc)-OBzl
EINECS Contact for details

Quality Control

Our L-Lysine, N6-[(1,1-Dimethylethoxy)Carbonyl]-N2-[(Phenylmethoxy)Carbonyl]-, Phenylmethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and chiral integrity, meeting the exacting standards required for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC) and spectroscopic confirmation are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition. For long-term storage, consider storing under an inert atmosphere.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Optical Rotation [α]D20 Contact for details
Chiral Purity (HPLC) ≥ 99.0% (L-isomer)
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals (as Pb) ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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