Description

8-o-Methyl-7,9-Di-o-Acetyl-n-Glycolylneuraminic Acid is a chemically modified derivative of sialic acid, a critical carbohydrate moiety in glycobiology and pharmaceutical research. This high-purity intermediate is essential for the synthesis of complex glycoconjugates and for studying sialic acid-dependent biological recognition processes. It is primarily utilized by research institutions and pharmaceutical companies engaged in advanced glycoscience, vaccine development, and the production of novel therapeutic agents.

Application

• Glycoconjugate Synthesis: A key building block for the chemical and enzymatic synthesis of complex oligosaccharides, glycopeptides, and glycolipids.
• Pharmaceutical Intermediates: Serves as a critical precursor in the research and development of sialidase inhibitors, antiviral drugs, and anti-inflammatory agents.
• Biochemical Research: Used as a standard or substrate in studies of sialyltransferases, neuraminidases, and other enzymes involved in sialic acid metabolism.
• Vaccine Development: Employed in the design and production of conjugate vaccines where specific sialic acid structures are required for antigenicity.
• Diagnostic Reagent Manufacturing: Utilized in the production of reagents for detecting pathogens or biomarkers that interact with sialylated structures.
• Cell Biology Studies: Applied in research investigating cell-cell interactions, signaling, and adhesion mediated by sialic acid-containing molecules.

Basic Information

Product Name	8-o-Methyl-7,9-Di-o-Acetyl-n-Glycolylneuraminic Acid
CAS No.	128885-13-2
Molecular Formula	C18H29NO13
Molecular Weight	467.42 g/mol
Synonyms	8-O-Methyl-7,9-di-O-acetyl-N-glycolylneuraminic acid; N-Glycolyl-8-O-methyl-7,9-di-O-acetylneuraminic acid; 8-Methyl-7,9-diacetyl-N-glycolylneuraminate; Modified Sialic Acid Derivative; Sialic Acid Methyl Acetyl Glycolyl Ester; Neu5Gc8Me7,9Ac; Research Grade Sialic Acid Analog
EINECS	Contact for details

Quality Control

Our 8-o-Methyl-7,9-Di-o-Acetyl-n-Glycolylneuraminic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.