Description

3H-Pyrazolo[3,4-D]Pyrimidin-3-One, 4-Amino-1,2-Dihydro- is a high-purity heterocyclic organic compound belonging to the pyrazolopyrimidine class, serving as a critical advanced pharmaceutical intermediate. Its value lies in its role as a sophisticated building block for the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. This product is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers focused on creating novel therapeutic agents, especially in oncology and kinase inhibitor development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of targeted kinase inhibitors and other small-molecule drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Biochemical Research: Serves as a core scaffold or precursor for developing enzyme inhibitors and probes in biochemical assays.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for heterocyclic chemistry and organic synthesis studies.
• Pre-clinical Development: Employed in the production of compounds for pre-clinical testing and toxicology studies.

Basic Information

Product Name	3H-Pyrazolo[3,4-D]Pyrimidin-3-One, 4-Amino-1,2-Dihydro-
CAS No.	128850-54-4
Molecular Formula	C5H5N5O
Molecular Weight	151.13 g/mol
Synonyms	4-Amino-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one; 4-Aminopyrazolo[3,4-d]pyrimidin-3(2H)-one; 4-Amino-1H-pyrazolo[3,4-d]pyrimidin-3(2H)-one; 4-Amino-1,2-dihydropyrazolo[3,4-d]pyrimidin-3-one; 4-Amino-3H-pyrazolo[3,4-d]pyrimidin-3-one; Pyrazolo[3,4-d]pyrimidin-3-one, 4-amino-1,2-dihydro-; 4-Amino-1H-pyrazolo[3,4-d]pyrimidin-3-ol (tautomer)
EINECS	Contact for details

Quality Control

Our 3H-Pyrazolo[3,4-D]Pyrimidin-3-One, 4-Amino-1,2-Dihydro- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.