Description

Suc-Ala-Gln-Pro-Phe-Pna CAS NO 128822-33-3 is a synthetic peptide substrate designed for biochemical and pharmaceutical research. This compound is critical for studying enzyme kinetics and inhibition, particularly for proteases like chymotrypsin and related serine proteases. It is an essential tool for researchers and developers in the fields of drug discovery, enzymology, and diagnostic assay development, where precise substrate specificity is required.

Application

• Protease Activity Assays: Used as a chromogenic substrate to measure the activity and kinetics of serine proteases, including chymotrypsin and elastase.
• Drug Discovery Screening: Employed in high-throughput screening (HTS) platforms to identify and characterize novel protease inhibitors for therapeutic development.
• Enzyme Mechanism Studies: Facilitates research into enzyme-substrate interactions, catalytic mechanisms, and specificity profiling.
• Diagnostic Reagent Development: Serves as a key component in developing colorimetric diagnostic kits for detecting protease activity in clinical samples.
• Biochemical Research: A standard reagent for academic and industrial laboratories studying protein digestion, peptide metabolism, and signal transduction pathways.
• Quality Control in Biopharma: Used to test the activity and consistency of enzyme preparations used in biomanufacturing processes.

Basic Information

Product Name	Suc-Ala-Gln-Pro-Phe-Pna
CAS No.	128822-33-3
Molecular Formula	C₃₃H₄₂N₈O₁₁
Molecular Weight	726.74 g/mol
Synonyms	Suc-AQPFP-pNA; N-Succinyl-Ala-Gln-Pro-Phe-p-nitroanilide; Succinyl-Alanyl-Glutaminyl-Prolyl-Phenylalanyl-p-Nitroanilide; Chymotrypsin Substrate Suc-AQPFP-pNA; Protease Substrate 128822-33-3; Suc-Ala-Gln-Pro-Phe-pNA; N-Succinyl-Ala-Gln-Pro-Phe-pNA; Suc-AQPFP-pNA Substrate
EINECS	Contact for details

Quality Control

Our Suc-Ala-Gln-Pro-Phe-Pna is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and performance in standard assay conditions. We support compliance with relevant GMP guidelines for research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water
Functional Activity	Conforms in standard chymotrypsin assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.