Description

Suc-Ala-Ile-Pro-Phe-Pna is a synthetic chromogenic peptide substrate designed for enzymatic research and assay development. This compound is a critical tool for studying and quantifying the activity of specific proteolytic enzymes, particularly in biochemical and pharmaceutical research. It is primarily utilized by scientists and quality control laboratories in the pharmaceutical, biotechnology, and diagnostic industries for high-throughput screening and enzyme kinetics studies. The product is supplied with a guaranteed high level of purity and batch-to-batch consistency to ensure reliable and reproducible experimental results.

Application

• Enzyme Activity Assays: Primary substrate for the spectrophotometric detection and quantification of protease activity, such as chymotrypsin or subtilisin.
• Biochemical Research: Used in kinetic studies to determine enzyme inhibition constants (Ki) and catalytic efficiency (kcat/Km).
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) platforms to identify and characterize novel protease inhibitors as potential drug candidates.
• Diagnostic Development: Serves as a key component in developing in-vitro diagnostic tests for conditions related to abnormal protease levels.
• Quality Control: Used in biomanufacturing to monitor the presence and activity of specific enzymes during production processes.

Basic Information

Product Name	Suc-Ala-Ile-Pro-Phe-PNA
CAS No.	128802-79-9
Molecular Formula	C34H44N6O9
Molecular Weight	680.75 g/mol
Synonyms	N-Succinyl-Ala-Ile-Pro-Phe-p-nitroanilide; Suc-AIPF-pNA; Suc-Ala-Ile-Pro-Phe-pNA; N-Succinyl-Alanyl-Isoleucyl-Prolyl-Phenylalanyl-p-Nitroanilide; Protease Substrate IV; Chromogenic Substrate for Chymotrypsin; Suc-AIPF-PNA
EINECS	Contact for details

Quality Control

Our Suc-Ala-Ile-Pro-Phe-Pna is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation by mass spectrometry (MS) and infrared spectroscopy (IR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Identification (IR)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.