Description

Suc-Ala-Leu-Pro-Phe-Pna CAS NO 128802-78-8 is a synthetic peptide substrate designed for biochemical research and pharmaceutical development. This compound is a critical tool for studying and quantifying the activity of specific proteolytic enzymes, particularly in the context of drug discovery and diagnostic assay development. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for high-throughput screening and enzyme kinetics studies.

Application

• Enzyme Activity Assays: A specific chromogenic substrate for measuring the activity of proteases like chymotrypsin, elastase, and related serine proteases in vitro.
• Drug Discovery & Screening: Used in high-throughput screening (HTS) platforms to identify and characterize potential enzyme inhibitors as novel therapeutic candidates.
• Biochemical Research: Fundamental tool for studying enzyme kinetics, substrate specificity, and catalytic mechanisms in academic and industrial R&D laboratories.
• Diagnostic Kit Development: Employed in the formulation of diagnostic reagents and kits for detecting specific enzyme levels associated with pathological conditions.
• Quality Control in Biologics: Acts as a reference standard or assay component for monitoring the presence and activity of process-related enzymes during biopharmaceutical manufacturing.

Basic Information

Product Name	Suc-Ala-Leu-Pro-Phe-Pna
CAS No.	128802-78-8
Molecular Formula	C34H44N6O9
Molecular Weight	680.75 g/mol
Synonyms	N-Succinyl-Ala-Leu-Pro-Phe-p-nitroanilide; Suc-A-L-P-F-pNA; Suc-ALPF-pNA; N-Succinyl-Alanyl-Leucyl-Prolyl-Phenylalanyl-p-Nitroanilide; Protease Substrate Suc-ALPF-pNA; Chymotrypsin Substrate I; Chromogenic Substrate for Elastase
EINECS	Contact for details

Quality Control

Our Suc-Ala-Leu-Pro-Phe-Pna is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC purity analysis, mass spectrometry (MS) confirmation, and functional activity validation. A detailed Certificate of Analysis (COA) documenting identity, purity, and assay performance is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water
Functional Activity	Conforms to reference standard

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.