Description

Ac-Thr-Ile-Nle-((R))-Nle-Gln-Arg-Nh2 is a synthetic peptide sequence of significant interest in advanced biochemical research and development. This compound matters as a specialized building block for studying protein-protein interactions, enzyme specificity, and for the development of novel therapeutic agents and diagnostic tools. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors for applications in peptide synthesis, drug discovery, and biochemical assay development.

Application

• Pharmaceutical Research: As a key intermediate or reference standard in the discovery and development of novel peptide-based therapeutics.
• Biochemical Assays: Utilized as a substrate or inhibitor in enzymatic studies to investigate specific biological pathways and mechanisms.
• Peptide Synthesis: Serves as a crucial building block for the solid-phase or solution-phase synthesis of longer, more complex peptide chains.
• Structure-Activity Relationship (SAR) Studies: Used to analyze how modifications to peptide sequences affect biological activity and binding affinity.
• Diagnostic Development: Potential use in the creation of reagents for immunoassays or other diagnostic tests targeting specific protein epitopes.
• Academic Research: A valuable tool in university and institutional labs for fundamental research in biochemistry, molecular biology, and medicinal chemistry.

Basic Information

Item	Details
Product Name	Ac-Thr-Ile-Nle-((R))-Nle-Gln-Arg-Nh2
CAS No.	128657-47-6
Molecular Formula	C34H62N12O10
Molecular Weight	774.93 g/mol
Synonyms	Acetyl-Threonyl-Isoleucyl-Norleucyl-((R))-Norleucyl-Glutaminyl-Argininamide; Ac-T-I-Nle-((R))-Nle-Q-R-NH2; N-Acetyl-L-threonyl-L-isoleucyl-L-norleucyl-((R))-L-norleucyl-L-glutaminyl-L-argininamide; Peptide Sequence Ac-Thr-Ile-Nle-((R))-Nle-Gln-Arg-NH2; CAS 128657-47-6; Ac-T-I-Nle-(R)-Nle-Q-R-NH2; Ac-Thr-Ile-Nle-(R)-Nle-Gln-Arg-amide
EINECS	Contact for details

Quality Control

Our Ac-Thr-Ile-Nle-((R))-Nle-Gln-Arg-Nh2 is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. All products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This hygroscopic and easily oxidized material should be stored under an inert atmosphere (e.g., argon or nitrogen) and allowed to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, DMSO, acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.