Description

Antigen Sm23, Schistosoma is a purified protein antigen derived from the Schistosoma mansoni parasite, specifically the Sm23 membrane protein. This high-purity biological reagent is critical for research, diagnostic development, and vaccine studies targeting schistosomiasis, a major neglected tropical disease. It is an essential tool for immunologists, parasitologists, and diagnostic manufacturers engaged in the fight against parasitic infections.

Application

• Immunoassay Development: As a key coating antigen or standard in ELISA and other serological tests for detecting anti-Schistosoma antibodies.
• Vaccine Research: Used as an immunogen or target antigen in preclinical studies to evaluate vaccine candidates and immune responses.
• Diagnostic Kit Production: A vital raw material for the commercial manufacturing of in-vitro diagnostic (IVD) kits for schistosomiasis.
• Basic Research: Employed in immunological studies to understand host-parasite interactions, immune evasion, and pathogenesis.
• Antibody Specificity Testing: Used to characterize and validate the specificity of monoclonal and polyclonal antibodies.
• Quality Control Reference: Serves as a reference standard for the quality control of other diagnostic reagents and assays.

Basic Information

Product Name	Antigen Sm23, Schistosoma
CAS No.	128634-83-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Sm23 Antigen; Schistosoma mansoni 23 kDa Integral Membrane Protein Antigen; Sm23 Protein; Schistosome Antigen Sm23; Tegument Antigen Sm23; Schistosoma Diagnostic Antigen; 23 kDa Membrane Protein Antigen
EINECS	Contact for details

Quality Control

Our Antigen Sm23 is produced and tested under stringent quality management systems. Each batch is characterized for identity, purity, and biological activity using advanced analytical techniques including SDS-PAGE, Western Blot, and HPLC. A comprehensive Certificate of Analysis (COA) detailing purity, protein concentration, endotoxin levels, and functionality data is provided with every shipment to ensure reproducible performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized material at -20°C or below. Reconstituted aliquots should be stored at -70°C or lower and avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Western Blot)	Positive reaction with specific anti-Sm23 antibody
Purity (SDS-PAGE)	≥ 90%
Protein Content (BCA)	≥ 90% of stated weight
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity (ELISA)	Reactive with standard positive control serum
Solubility	Soluble in PBS or appropriate aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.