Description

Hiv Envelope Protein Gp41 (519-541) is a synthetic peptide fragment corresponding to a specific region of the HIV-1 envelope glycoprotein gp41. This compound is a critical research reagent for studying viral entry mechanisms, host-pathogen interactions, and for the development of novel diagnostic and therapeutic strategies against HIV/AIDS. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on virology and immunology.

Application

• Biochemical Research: Used as a key antigen in studies of HIV-1 fusion and entry into host cells.
• Immunoassay Development: Serves as a coating antigen or standard in ELISA and other immunoassays for antibody detection.
• Vaccine Research: Investigated as a potential component in epitope-based vaccine candidates targeting the gp41 protein.
• Antiviral Drug Screening: Employed in high-throughput screening assays to identify and characterize novel fusion inhibitor compounds.
• Structural Biology: Used in NMR and X-ray crystallography studies to determine the three-dimensional structure of gp41 domains.
• Antibody Characterization: Essential for evaluating the specificity and neutralizing activity of monoclonal antibodies against HIV.

Basic Information

Product Name	Hiv Envelope Protein Gp41 (519-541)
CAS No.	128631-86-7
Molecular Formula	C115H177N33O34S
Molecular Weight	~2565.9 g/mol
Synonyms	HIV-1 gp41 (519-541); gp41 Peptide (519-541); HIV Envelope Glycoprotein gp41 Fragment; HIV-1 IIIB gp41 (519-541); Synthetic gp41 Peptide; AIDS Virus Envelope Protein Peptide; HIV Fusion Peptide Derivative; HGP-30 related peptide
EINECS	Contact for details

Quality Control

Our Hiv Envelope Protein Gp41 (519-541) is manufactured under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is characterized by advanced analytical techniques including HPLC and Mass Spectrometry. Certificates of Analysis (COA) detailing purity, identity, and peptide content are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This hygroscopic and easily oxidized material should be handled under inert atmosphere when possible and allowed to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Amino Acid Composition	Conforms to theoretical values
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.