Description

1H-Cyclopropa[4,5]Pyrido[2,3-D]Pyrimidine (9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of novel drug candidates targeting various therapeutic areas. It is primarily sought after by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the development of innovative small-molecule therapies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic agents.
• Chemical Biology Probes: Serves as a core scaffold for developing molecular probes to study biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional laboratories for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1H-Cyclopropa[4,5]Pyrido[2,3-D]Pyrimidine (9Ci)
CAS No.	128447-00-7
Molecular Formula	C9H5N3
Molecular Weight	155.16 g/mol
Synonyms	1H-Cyclopropa[4,5]pyrido[2,3-d]pyrimidine; 1H-Cyclopropa[4,5]pyrido[2,3-d]pyrimidine (9CI); Cyclopropa[4,5]pyrido[2,3-d]pyrimidine, 1H-; 1H-Cyclopropa[4,5]pyrido[2,3-d]pyrimidine; 1H-Cyclopropa[4,5]pyrido[2,3-d]pyrimidine (9CI); 128447-00-7; Pyrido[2,3-d]pyrimidine, 1H-cyclopropa[4,5]-
EINECS	Contact for details

Quality Control

Our 1H-Cyclopropa[4,5]Pyrido[2,3-D]Pyrimidine (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.