Description

C12-Sphingosine CAS NO 128427-86-1 is a synthetic, medium-chain sphingoid base, a key structural analog and precursor in lipid biochemistry. This compound matters for researchers and manufacturers as it provides a more soluble and manageable alternative to longer-chain natural sphingosines for studying and modulating sphingolipid metabolism and signaling pathways. It is primarily needed by the life science research, pharmaceutical development, and cosmetic industries for applications in cell biology studies, drug discovery, and advanced skincare formulations.

Application

• Biochemical Research: A critical tool for investigating the role of sphingolipids in cell signaling, apoptosis, and membrane biology.
• Pharmaceutical Intermediates: Serves as a key synthetic building block for the development of novel therapeutics targeting metabolic and inflammatory diseases.
• Cosmetic Actives: Used in advanced skincare formulations for its potential role in modulating skin barrier function and cellular renewal.
• Enzyme Substrate/Inhibitor Studies: Employed in vitro to study the activity of enzymes like ceramide synthases and sphingosine kinases.
• Lipidomics Standards: Acts as a quantitative and qualitative standard in mass spectrometry-based lipidomic analysis.
• Cell Culture & Media Supplements: Utilized in specialized cell culture media to study lipid-mediated cellular processes.

Basic Information

Product Name	C12-Sphingosine
CAS No.	128427-86-1
Molecular Formula	C12H25NO2
Molecular Weight	215.33 g/mol
Synonyms	D-erythro-C12-Sphingosine; D-erythro-2-Amino-1,3-dihydroxy-4-dodecene; (2S,3R,4E)-2-Amino-3-hydroxy-4-dodecen-1-ol; 4-Dodecene-1,3-diol, 2-amino-, (2S,3R,4E)-; C12-Sphingosine base; N-Dodecanoylsphingosine precursor; Medium-chain sphingoid base
EINECS	Contact for details

Quality Control

Our C12-Sphingosine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-purity research and development standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. Due to its hygroscopic (moisture-sensitive) nature, containers should be sealed under an inert atmosphere after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.