Description

H-Tyr-Ser-NH2 HCl is a synthetic dipeptide derivative, specifically the C-terminal amide of the tyrosine-serine sequence. This compound is a crucial building block in peptide synthesis and pharmaceutical research, valued for its role in creating more stable and biologically active peptide analogs. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in advanced peptide chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the solid-phase and solution-phase synthesis of complex therapeutic peptides.
• Biochemical Research: Used as a standard or substrate in enzymatic studies and structure-activity relationship (SAR) investigations.
• Neuropeptide Analog Development: A fundamental component for constructing analogs of endogenous peptides that contain the Tyr-Ser motif.
• Cosmeceutical Peptide Synthesis: Incorporated into the design of bioactive peptides for skincare applications targeting specific cellular pathways.
• Academic Research: Employed in university and institutional labs for teaching advanced peptide chemistry and medicinal chemistry principles.
• Process Development: Used in scaling up and optimizing synthetic routes for peptide-based Active Pharmaceutical Ingredients (APIs).

Basic Information

Product Name	H-Tyr-Ser-NH2 HCl
CAS No.	128245-94-3
Molecular Formula	C12H18N3O4 • HCl
Molecular Weight	305.75 g/mol (Free base: 268.29)
Synonyms	L-Tyrosyl-L-serinamide hydrochloride; Tyr-Ser-NH2 • HCl; H-Tyr-Ser-NH2 • HCl; Tyrosine-Serine amide hydrochloride; L-Tyrosine-L-serine amide hydrochloride; TYR-SER-NH2 HYDROCHLORIDE; NSC 760439; ZINC000003870367
EINECS	Contact for details

Quality Control

Our H-Tyr-Ser-NH2 HCl is produced under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via mass spectrometry and NMR. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Assay (Titration)	97.0% - 102.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.