Description

L-Prolinamide,D-Histidyl-, Dihydrobromide is a high-purity, non-natural dipeptide derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and a model substrate for studying enzyme specificity, peptide stability, and receptor-ligand interactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide synthesis, proteomics, and the discovery of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex peptide-based drugs and bioactive molecules.
• Biochemical Research: Used as a standard or substrate in enzymatic studies, particularly those involving peptidases and proteases.
• Peptide Library Construction: An essential component for creating diverse peptide libraries used in high-throughput screening for drug discovery.
• Structure-Activity Relationship (SAR) Studies: Employed to investigate the impact of specific amino acid modifications on biological activity and peptide conformation.
• Academic & Industrial R&D: Fundamental tool in university and corporate laboratories for advancing knowledge in peptide chemistry and medicinal chemistry.

Basic Information

Product Name	L-Prolinamide,D-Histidyl-, Dihydrobromide
CAS No.	128083-56-7
Molecular Formula	C11H18Br2N6O2
Molecular Weight	434.11 g/mol
Synonyms	D-His-L-Pro-NH2 dihydrobromide; H-D-His-L-Pro-NH2·2HBr; Histidylprolinamide dihydrobromide; (2S)-1-[(2R)-2-Amino-3-(1H-imidazol-4-yl)propanoyl]pyrrolidine-2-carboxamide dihydrobromide; D-Histidyl-L-prolinamide dihydrobromide; L-Prolinamide, D-histidyl-, dihydrobromide; Pro-His-NH2·2HBr
EINECS	Contact for details

Quality Control

Our L-Prolinamide,D-Histidyl-, Dihydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.