Description

Ethanone, 1-(2-Amino-5-Fluorophenyl)-2-Chloro- (9Ci) is a high-purity, halogenated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where its specific substitution pattern enables precise molecular construction. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, particularly those requiring a fluorinated aniline moiety.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances bioactivity and stability.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transport or host materials in electronic applications.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for transition metal catalysis and asymmetric synthesis.
• Fluorescent Dye and Pigment Precursor: Utilized in the synthesis of specialized dyes and pigments for high-performance imaging and coloring applications.
• Academic and Contract Research: A valuable reagent for methodological development and exploratory chemistry in research laboratories.

Basic Information

Product Name	Ethanone, 1-(2-Amino-5-Fluorophenyl)-2-Chloro- (9Ci)
CAS No.	128076-64-2
Molecular Formula	C8H7ClFNO
Molecular Weight	187.60 g/mol
Synonyms	2'-Amino-5'-fluoro-2-chloroacetophenone; 1-(2-Amino-5-fluorophenyl)-2-chloroethanone; 2-Chloro-1-(2-amino-5-fluorophenyl)ethan-1-one; 5-Fluoro-2-amino-α-chloroacetophenone; α-Chloro-2-amino-5-fluoroacetophenone; 2-Amino-5-fluorophenyl chloromethyl ketone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(2-Amino-5-Fluorophenyl)-2-Chloro- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.