Description

Lhrh, Ac-2-Nal(1)-4-Cl-Phe(2)-Trp(3)-Ser(Rha)(6)-Azglynh2(10)- CAS NO 127932-90-5 is a synthetic, modified peptide analog of Gonadotropin-Releasing Hormone (GnRH). This compound is engineered for enhanced stability and specific receptor binding affinity, making it a critical research tool and a potential precursor for therapeutic development. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on endocrinology, oncology, and reproductive medicine.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active ingredient in preclinical studies for novel hormone therapies.
• Endocrinology Studies: Used to investigate the hypothalamic-pituitary-gonadal axis, receptor-ligand interactions, and hormone signaling pathways.
• Oncology Research: Explored in the development of targeted therapies for hormone-dependent cancers, such as prostate and breast cancer.
• Reproductive Medicine: Applied in research concerning fertility treatments and the regulation of reproductive hormones.
• Biochemical Assay Development: Employed as a calibrant or competitive ligand in immunoassays (ELISA, RIA) and binding studies.
• Peptide Chemistry & Conjugation: Acts as a sophisticated substrate for studying peptide stability, modification techniques, and prodrug strategies.

Basic Information

Product Name	Lhrh, Ac-2-Nal(1)-4-Cl-Phe(2)-Trp(3)-Ser(Rha)(6)-Azglynh2(10)- CAS NO 127932-90-5
CAS No.	127932-90-5
Molecular Formula	C64H83ClN16O13
Molecular Weight	1287.9 g/mol
Synonyms	Ac-D-2-Nal-4-Cl-D-Phe-D-3-Pal-Ser-Tyr-D-Lys-Leu-Arg-Pro-AzGly-NH2; GnRH Antagonist Analog; Luteinizing Hormone-Releasing Hormone Antagonist; Modified GnRH Peptide; Azagly-NH10 LHRH Antagonist; [Ac-D-2-Nal1, D-4-Cl-Phe2, D-3-Pal3, Ser4, D-Lys6, AzGly10]-LHRH; 127932-90-5; LHRH (antagonist)
EINECS	Contact for details

Quality Control

Our Lhrh peptide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing all critical quality attributes to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 8.0%
Peptide Content	≥ 80.0%
Amino Acid Analysis	Within ± 10% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.