Description

C-Type Natriuretic Peptide (32-53) (Human, Porcine, Rat) is a defined fragment of the C-type natriuretic peptide (CNP), a key member of the natriuretic peptide family. This high-purity peptide is essential for cardiovascular and endocrinology research, serving as a critical reference standard and active pharmaceutical ingredient (API) intermediate. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing novel therapeutics for conditions like hypertension, heart failure, and skeletal growth disorders. The compound is supplied with a CAS registry number of 127869-51-6.

Application

• Biomedical Research Standard: Used as a precise reference material in quantitative assays (e.g., ELISA, RIA) to study CNP biology and receptor binding.
• Pharmacological Studies: Critical for in vitro and in vivo research investigating the vasodilatory, diuretic, and natriuretic effects of CNP fragments.
• Drug Discovery & Development: Serves as a key intermediate or starting material in the synthesis of peptide-based therapeutics targeting natriuretic peptide receptors.
• Diagnostic Kit Development: Employed in the calibration and validation of diagnostic kits designed to measure CNP levels in biological samples.
• Cell Signaling Pathway Analysis: A vital tool for elucidating the role of CNP in intracellular signaling cascades related to cardiovascular function and bone growth.
• Quality Control in Manufacturing: Acts as a system suitability standard in the QC laboratories of pharmaceutical companies producing related peptide drugs.

Basic Information

Product Name	C-Type Natriuretic Peptide (32-53) (Human, Porcine, Rat)
CAS No.	127869-51-6
Molecular Formula	C106H172N34O31S2
Molecular Weight	2418.8 g/mol
Synonyms	CNP (32-53); C-Type Natriuretic Peptide fragment 32-53; Human CNP-22 (32-53); Porcine CNP-22 (32-53); Rat CNP-22 (32-53); Natriuretic Peptide C (32-53); CNP-22 (32-53); CNP Fragment 32-53
EINECS	Contact for details

Quality Control

Our C-Type Natriuretic Peptide (32-53) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. While produced to meet exacting internal standards, specifications can be aligned with specific pharmacopeial requirements (e.g., USP) for advanced applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate at -20°C. Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.