Description

Z-Pro-Phe-Nh2 CAS NO 127861-61-4 is a protected dipeptide derivative, specifically a Z-protected prolyl-phenylalanine amide, serving as a crucial building block in advanced organic synthesis. This compound is valued for its role in constructing complex peptide sequences and as a chiral intermediate in pharmaceutical research and development. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the synthesis of bioactive peptides, protease inhibitors, and other specialized organic molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Protease Inhibitor Research: Used in the development and study of inhibitors targeting specific proteolytic enzymes.
• Solid-Phase Peptide Synthesis (SPPS): A protected dipeptide unit for the sequential assembly of longer, more complex peptide chains.
• Biochemical Research: Serves as a substrate or standard in enzymatic studies and metabolic pathway investigations.
• Chiral Pool Synthesis: Provides a source of defined stereochemistry for the asymmetric synthesis of non-peptide molecules.
• Fine Chemical Production: Intermediate in the custom synthesis of specialty chemicals for agrochemical and material science applications.

Basic Information

Item	Detail
Product Name	Z-Pro-Phe-Nh2
CAS No.	127861-61-4
Molecular Formula	C22H25N3O4
Molecular Weight	395.45 g/mol
Synonyms	Z-Pro-Phe-NH2; N-Benzyloxycarbonyl-L-prolyl-L-phenylalaninamide; CBZ-L-Prolyl-L-phenylalaninamide; Z-L-Pro-L-Phe-NH2; Benzyloxycarbonyl-L-prolyl-L-phenylalaninamide; (S)-N-((S)-1-((Benzyloxy)carbonyl)pyrrolidine-2-carbonyl)-2-phenylacetamide; N-Cbz-L-prolyl-L-phenylalaninamide; L-Phenylalaninamide, N-[(phenylmethoxy)carbonyl]-L-prolyl-
EINECS	Contact for details

Quality Control

Our Z-Pro-Phe-Nh2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.