Description

(R)-1-[3-(Trifluoromethyl)Phenyl]Ethylamine is a high-value chiral amine building block characterized by its trifluoromethylphenyl group, which imparts unique physicochemical properties. This compound is essential for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its stereochemistry and fluorine content are critical for biological activity and metabolic stability. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) drugs and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced efficacy.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	(R)-1-[3-(Trifluoromethyl)Phenyl]Ethylamine
CAS No.	127852-30-6
Molecular Formula	C9H10F3N
Molecular Weight	189.18 g/mol
Synonyms	(R)-α-Methyl-3-(trifluoromethyl)benzeneethanamine; (R)-1-(3-Trifluoromethylphenyl)ethylamine; (R)-3'-(Trifluoromethyl)phenethylamine; (R)-1-[3-(Trifluoromethyl)phenyl]ethanamine; (R)-1-(3-(Trifluoromethyl)phenyl)ethan-1-amine; (R)-3-(Trifluoromethyl)phenethylamine; (R)-TFMPEA; (R)-1-(m-Trifluoromethylphenyl)ethylamine
EINECS	Contact for details

Quality Control

Our (R)-1-[3-(Trifluoromethyl)Phenyl]Ethylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.