Description

3,4-Bis-Difluoromethoxy-Benzaldehyde is a high-purity fluorinated aromatic aldehyde building block, identified by CAS No. 127842-54-0. This compound is valued for its unique difluoromethoxy substituents, which enhance its metabolic stability and lipophilicity, making it a critical intermediate in advanced synthesis. It is primarily sought by R&D and production teams in the pharmaceutical and agrochemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms contribute to improved biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance display technologies.
• Functional Polymer Monomer: Incorporated into specialty polymers to impart unique chemical resistance and thermal stability properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions and as a precursor for other functionalized benzaldehyde derivatives in fine chemical production.

Basic Information

Product Name	3,4-Bis-Difluoromethoxy-Benzaldehyde
CAS No.	127842-54-0
Molecular Formula	C10H8F4O3
Molecular Weight	252.16 g/mol
Synonyms	3,4-Bis(difluoromethoxy)benzaldehyde; Benzaldehyde, 3,4-bis(difluoromethoxy)-; 3,4-Difluoromethoxybenzaldehyde (ambiguous); 127842-54-0; Aldehyde C10 H8 F4 O3; 3,4-Bis(difluoromethoxy)benzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 3,4-Bis-Difluoromethoxy-Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.