Description

H-Tyr(Allyl)-Ome is a protected tyrosine derivative, specifically the O-allyl ether of methyl L-tyrosine, with the CAS registry number 127802-97-5. This compound is a critical building block in modern peptide synthesis, offering a versatile protecting group strategy that is orthogonal to standard Fmoc/Boc chemistry. It is essential for researchers and manufacturers in pharmaceutical development and biotechnology who require high-purity, specialized amino acid derivatives for constructing complex peptide and protein-based therapeutics.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of tyrosine residues with orthogonal side-chain protection.
• Solution-Phase Peptide Synthesis: Used in the synthesis of complex peptides, hormones, and bioactive sequences where selective deprotection is required.
• Pharmaceutical Research & Development: Serves as a crucial building block for developing novel peptide drugs, diagnostic agents, and targeted therapeutics.
• Chemical Biology & Bioconjugation: The allyl protecting group can be utilized in further functionalization or as a handle for site-specific conjugation to other molecules or surfaces.
• Protecting Group Chemistry: A valuable reagent for studying and applying advanced protecting group strategies in organic and medicinal chemistry.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	H-Tyr(Allyl)-Ome
CAS No.	127802-97-5
Molecular Formula	C13H17NO3
Molecular Weight	235.28 g/mol
Synonyms	Methyl L-tyrosine O-allyl ether; L-Tyrosine, O-(2-propen-1-yl)-, methyl ester; Methyl O-allyl-L-tyrosinate; H-Tyr(All)-OMe; Fmoc-Tyr(All)-OH precursor; Tyrosine(Allyl)-methyl ester; O-Allyl-L-tyrosine methyl ester; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(2-propen-1-yl)-L-tyrosine methyl ester (related protected form)
EINECS	Contact for details

Quality Control

Our H-Tyr(Allyl)-Ome is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm enantiomeric purity, and spectroscopic identification (NMR, IR, MS). We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.