Description

Biotinyl-Tryptophyl-Leucyl-β-Alanine is a synthetic peptide derivative that combines the vitamin biotin with a specific amino acid sequence. This compound is valued for its high specificity and affinity in biochemical research and diagnostic applications. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical development, and in-vitro diagnostics sectors for targeted binding and detection systems.

Application

• Bioconjugation & Probe Development: Used as a high-affinity biotinylated probe or linker for conjugating biomolecules to avidin/streptavidin-based detection systems in assays.
• Diagnostic Assays: Serves as a critical component in the development of ELISA, lateral flow tests, and other immunoassays for enhanced sensitivity and specificity.
• Affinity Purification: Employed in the purification of proteins, antibodies, or other target molecules using streptavidin-coated beads or columns.
• Cell Biology Research: Used for labeling cell surface receptors or intracellular targets for visualization and tracking studies via fluorescence or other detection methods.
• Drug Delivery Systems: Investigated as a targeting moiety in drug conjugates to direct therapeutic agents to specific cells or tissues.
• Material Science: Functionalizes surfaces (e.g., biosensors, microarrays) to create bioactive interfaces for research and diagnostic platforms.

Basic Information

Product Name	Biotinyl-Tryptophyl-Leucyl-β-Alanine
CAS No.	127745-41-9
Molecular Formula	C33H48N8O7S
Molecular Weight	700.85 g/mol
Synonyms	Biotin-Trp-Leu-β-Ala-OH; Biotin-Tryptophan-Leucine-β-Alanine; Biotin-W-L-β-Ala; H-Biotin-Trp-Leu-β-Ala-OH; (3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl 5-[(2S)-2-[(2S)-2-amino-4-methylpentanamido]-3-(1H-indol-3-yl)propanamido]pentanoate; Biotinylated Tetrapeptide; Biotin-Trp-Leu-βAla
EINECS	Contact for details

Quality Control

Our Biotinyl-Tryptophyl-Leucyl-β-Alanine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and diagnostic applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation. Store in a cool, dry place.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥95.0%
Assay	≥97.0% (on anhydrous basis)
Water Content (KF)	≤5.0%
Single Impurity (HPLC)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.