Description

Oxytocin, Glu(Nhnh2)(4)- CAS NO 127716-65-8 is a chemically modified analog of the neuropeptide hormone oxytocin, featuring a specific hydrazide substitution on the glutamic acid residue. This modification is of significant interest for advanced biochemical and pharmaceutical research, offering a unique tool for studying receptor interactions and developing novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical developers focused on neuroendocrinology, peptide chemistry, and drug discovery.

Application

• Biochemical Research: A critical tool for investigating the structure-activity relationships (SAR) of oxytocin and its receptor binding mechanisms.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the R&D of novel peptide-based therapeutics targeting neurological and reproductive disorders.
• Probe Synthesis: Used in the synthesis of affinity probes, fluorescent tags, or bioconjugates for cellular imaging and diagnostic assay development.
• Enzyme Studies: Employed in studies involving peptidases and other enzymes that process or modify neuropeptide hormones.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in peptide manufacturing.

Basic Information

Product Name	Oxytocin, Glu(Nhnh2)(4)- CAS NO 127716-65-8
CAS No.	127716-65-8
Molecular Formula	C₄₃H₆₆N₁₂O₁₂S₂
Molecular Weight	1007.2 g/mol
Synonyms	4-Glutamylhydrazide-oxytocin; [Glu(NHNH₂)⁴]-Oxytocin; Oxytocin (4-Glu(NHNH₂)); Oxytocin analog (Glu⁴→Glu(NHNH₂)); H-Cys-Tyr-Ile-Gln(NHNH₂)-Asn-Cys-Pro-Leu-Gly-NH₂ (disulfide bridge: 1-6); 127716-65-8; Oxytocin hydrazide derivative
EINECS	Contact for details

Quality Control

Our Oxytocin, Glu(Nhnh2)(4)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Amino Acid Analysis	Within ±10% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.