Description

Pyrimidine, 4,6-Bis(Difluoromethoxy)-2-Methyl- (9Ci) is a specialized fluorinated pyrimidine derivative, a high-value intermediate designed for advanced chemical synthesis. This compound matters for its role in introducing difluoromethoxy and methyl-substituted pyrimidine scaffolds, which are critical for modulating the biological activity and physicochemical properties of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly for antiviral, anticancer, and central nervous system (CNS) targeted therapies.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the fluorinated pyrimidine core can enhance efficacy and environmental profile.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the development of specialty polymers and advanced materials with unique electronic or surface properties.
• Chemical Synthesis Reagent: Employed in organic chemistry research for constructing complex heterocyclic systems and introducing fluorinated alkoxy groups.
• Ligand and Catalyst Development: Utilized in the design of novel ligands for catalysis or as a structural component in metal-organic frameworks (MOFs).

Basic Information

Product Name	Pyrimidine, 4,6-Bis(Difluoromethoxy)-2-Methyl- (9Ci)
CAS No.	127697-73-8
Molecular Formula	C8H6F4N2O2
Molecular Weight	238.14 g/mol
Synonyms	4,6-Bis(difluoromethoxy)-2-methylpyrimidine; 2-Methyl-4,6-bis(difluoromethoxy)pyrimidine; 4,6-Bis(difluoromethoxy)-2-methyl-pyrimidine; Pyrimidine, 4,6-bis(difluoromethoxy)-2-methyl-; 127697-73-8; 2-Methyl-4,6-di(difluoromethoxy)pyrimidine
EINECS	Contact for details

Quality Control

Our Pyrimidine, 4,6-Bis(Difluoromethoxy)-2-Methyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.