Description

Fmoc-L-Thr(β-D-Gal(Ac)4)-Oh CAS NO 127656-85-3 is a sophisticated, orthogonally protected amino acid derivative designed for advanced solid-phase peptide synthesis (SPPS). This compound is critical for researchers developing glycopeptides, as it enables the precise incorporation of a threonine residue bearing a fully acetylated galactose moiety. It is an essential building block for pharmaceutical R&D, particularly in the synthesis of complex therapeutic peptides, vaccines, and glycoprotein mimetics where site-specific glycosylation is required.

Application

• Glycopeptide Synthesis: A key intermediate for the solid-phase synthesis of complex glycopeptides with defined glycosylation patterns.
• Pharmaceutical Research: Used in the development of novel therapeutic peptides, anticancer agents, and vaccines that mimic natural glycoproteins.
• Bioconjugation & Probe Development: Serves as a building block for creating labeled peptides or bioconjugates for diagnostic and imaging applications.
• Chemical Biology Studies: Enables the study of glycosylation's role in protein folding, stability, and biological activity.
• Antibiotic Development: Applied in the research and synthesis of glycosylated antibiotic peptides.

Basic Information

Product Name	Fmoc-L-Thr(β-D-Gal(Ac)4)-Oh
CAS No.	127656-85-3
Molecular Formula	C38H43NO15
Molecular Weight	777.75 g/mol
Synonyms	Fmoc-Thr(Gal(Ac)4)-OH; N-α-Fmoc-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-L-threonine; Fmoc-L-threonine, O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-; Fmoc-Thr[β-D-Gal(Ac)4]-OH; Fmoc-Thr(Galβ(Ac)4)-OH; Fmoc-T[Gal(Ac)4]-OH; Glycosylated Fmoc-Threonine derivative; Acetylated Galactosyl-Threonine Fmoc amino acid
EINECS	Contact for details

Quality Control

Our Fmoc-L-Thr(β-D-Gal(Ac)4)-Oh is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and chiral integrity. We adhere to cGMP principles for advanced pharmaceutical intermediates, and our quality protocols are designed to meet the stringent requirements of global research and development laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 1.0%
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.