Description

Fananserin is a high-purity, research-grade chemical compound with the CAS number 127625-29-0. This compound is a selective serotonin receptor antagonist of significant interest in advanced pharmacological research and development. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers. Its well-defined chemical properties make it a critical intermediate and reference standard for developing and studying novel therapeutic agents targeting specific neurological pathways.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the discovery and development of new central nervous system (CNS) drugs.
• Neuropharmacology Studies: Used as a selective 5-HT2A and 5-HT2C receptor antagonist in preclinical research to investigate serotonin's role in various neurological functions and disorders.
• Biochemical Assay Development: Employed as a critical reagent in developing and validating high-throughput screening (HTS) assays for receptor binding studies.
• Academic & Institutional Research: Utilized in university and government laboratories for fundamental neuroscience research and published studies.
• Fine Chemical Synthesis: Acts as a sophisticated building block for the custom synthesis of more complex, targeted molecular entities in contract research organizations (CROs).
• Reference Material Production: Supplied as a certified reference material (CRM) for quality control and analytical method calibration in regulatory and analytical laboratories.

Basic Information

Product Name	Fananserin
CAS No.	127625-29-0
Molecular Formula	C23H24FN3O2S
Molecular Weight	425.52 g/mol
Synonyms	Fananserin; RP 62203; 4-Fluoro-N-[4-[4-(1,2,3,4-tetrahydro-2-naphthalenyl)-1-piperazinyl]butyl]benzenesulfonamide; 4-Fluoro-N-[4-[4-(1,2,3,4-tetrahydronaphthalen-2-yl)piperazin-1-yl]butyl]benzenesulfonamide; RP-62203; RP62203
EINECS	Contact for details

Quality Control

Our Fananserin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, identification by spectroscopic methods (IR, NMR), and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP guidelines for the production of research chemicals intended for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in a dark place to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.