Description

n-(3-Fluorobenzyl)-4-Methylaniline, 97% is a high-purity fluorinated aromatic amine building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and functional materials, where its specific fluorine substitution pattern can dramatically influence biological activity and material properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, where the fluorobenzyl moiety is a common pharmacophore.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the fluorine atom to enhance bioavailability and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials where fluorinated aromatic amines modify electronic and physical properties.
• Dye and Pigment Intermediate: Acts as a starting material for the manufacture of specialized fluorinated dyes and pigments with unique color fastness and spectral characteristics.
• Custom Synthesis and Contract Manufacturing: A valuable reagent for custom synthesis houses and CROs/CMOs developing proprietary compounds for clients across multiple industries.

Basic Information

Item	Details
Product Name	n-(3-Fluorobenzyl)-4-Methylaniline, 97%
CAS No.	127598-65-6
Molecular Formula	C14H14FN
Molecular Weight	215.27 g/mol
Synonyms	N-[(3-Fluorophenyl)methyl]-4-methylaniline; 4-Methyl-N-(3-fluorobenzyl)aniline; Benzenamine, N-[(3-fluorophenyl)methyl]-4-methyl-; 1-Fluoro-3-[(4-methylphenyl)aminomethyl]benzene; 3-[(4-Methylphenyl)aminomethyl]fluorobenzene; N-(3-Fluorobenzyl)-p-toluidine; 4-Methyl-N-(3-fluorobenzyl)benzenamine
EINECS	Contact for details

Quality Control

Our n-(3-Fluorobenzyl)-4-Methylaniline, 97% is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the specified standard. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to yellow solid or liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.