Description

3-Fluoro-4-Bromobenzyl Bromide is a versatile and highly reactive halogenated benzyl bromide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of halogen atoms, which enables selective functionalization for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated and brominated benzyl moiety.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the halogenated aromatic ring contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the creation of advanced polymers, liquid crystals, and organic electronic materials due to its ability to modify electronic properties.
• Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form biaryl and other complex structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems.

Basic Information

Product Name	3-Fluoro-4-Bromobenzyl Bromide
CAS No.	127425-73-4
Molecular Formula	C7H5Br2F
Molecular Weight	267.92 g/mol
Synonyms	1-(Bromomethyl)-3-fluoro-4-bromobenzene; 4-Bromo-3-fluorobenzyl Bromide; (4-Bromo-3-fluorophenyl)methyl Bromide; α-Bromo-4-bromo-3-fluorotoluene; 3-Fluoro-4-bromobenzylbromide; 3-Fluoro-4-bromophenylmethyl Bromide; 4-Bromo-3-fluoro-α-bromotoluene; 4-Bromo-3-fluorobenzyl bromide
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Bromobenzyl Bromide is produced under stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.