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T-Butyloxycarbonyl-Valyl-Alanyl-Leucyl-2-Aminoisobutyryl-Valyl-Alanyl-Leucyl-2-Aminoisobutyryl Methyl Ester CAS NO 127363-91-1


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CAS No.:127363-91-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

T-Butyloxycarbonyl-Valyl-Alanyl-Leucyl-2-Aminoisobutyryl-Valyl-Alanyl-Leucyl-2-Aminoisobutyryl Methyl Ester is a specialized, protected peptide derivative designed for advanced research and development in synthetic chemistry. This compound is a critical building block for the synthesis of complex peptide sequences, offering precise control over molecular structure and function. It is primarily utilized by pharmaceutical researchers, biochemists, and fine chemical manufacturers engaged in the development of novel therapeutic agents, peptide-based drugs, and biochemical probes.

Application

  • Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, sequential assembly of custom peptide chains in drug discovery.
  • Pharmaceutical Research & Development: Serves as a crucial precursor in the synthesis of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
  • Biochemical Tool Development: Used to create labeled or modified peptides for studying protein-protein interactions, enzyme mechanisms, and cellular pathways.
  • Proteomics and Structural Biology: Enables the synthesis of specific peptide fragments for antibody production, epitope mapping, and structural analysis.
  • Fine Chemical Synthesis: Employed in the production of high-value, complex organic molecules for specialized industrial and research applications.

Basic Information

Product Name T-Butyloxycarbonyl-Valyl-Alanyl-Leucyl-2-Aminoisobutyryl-Valyl-Alanyl-Leucyl-2-Aminoisobutyryl Methyl Ester
CAS No. 127363-91-1
Molecular Formula C46H82N8O13
Molecular Weight 931.2 g/mol
Synonyms Boc-Val-Ala-Leu-Aib-Val-Ala-Leu-Aib-OMe; Boc-V-A-L-Aib-V-A-L-Aib-OMe; (tert-Butoxycarbonyl)valylalanylleucyl-(2-aminoisobutyryl)valylalanylleucyl-(2-aminoisobutyryl) methyl ester; Protected Heptapeptide Methyl Ester; Aib-Containing Peptide Building Block; Boc-Protected Peptide Fragment
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Quality Control

Our T-Butyloxycarbonyl-Valyl-Alanyl-Leucyl-2-Aminoisobutyryl-Valyl-Alanyl-Leucyl-2-Aminoisobutyryl Methyl Ester is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and NMR for structural verification, to ensure it meets the exacting standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC/MS) Conforms to reference standard
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 2.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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