Description

5-Amino-7-(3-Amino-1-Piperidyl)-1-Cyclopropyl-6,8-Difluoro-4-Oxo-Quino Line-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of novel fluoroquinolone antibiotics, offering a key structural moiety for developing potent antimicrobial agents. It is primarily required by pharmaceutical R&D laboratories and API manufacturers targeting the development of next-generation antibacterial therapies.

Application

• Active Pharmaceutical Ingredient (API) Intermediate: A key synthetic precursor in the production of advanced fluoroquinolone antibiotics.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the design, synthesis, and screening of new antibacterial drug candidates.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the scale-up and commercial production of specialized APIs.
• Academic & Institutional Research: Utilized in university and institutional labs for studying structure-activity relationships (SAR) of quinolone-based compounds.
• Process Chemistry Development: Employed in optimizing synthetic routes for more efficient and cost-effective API manufacturing processes.

Basic Information

Product Name	5-Amino-7-(3-Amino-1-Piperidyl)-1-Cyclopropyl-6,8-Difluoro-4-Oxo-Quino Line-3-Carboxylic Acid
CAS No.	127294-71-7
Molecular Formula	C₁₈H₂₁F₂N₅O₃
Molecular Weight	393.39 g/mol
Synonyms	5-Amino-7-(3-amino-1-piperidinyl)-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 1-Cyclopropyl-6,8-difluoro-1,4-dihydro-5-amino-7-(3-amino-1-piperidinyl)-4-oxoquinoline-3-carboxylic acid; DW-116; Quinolone carboxylic acid derivative; Fluoroquinolone intermediate; Antibacterial intermediate; 3-Quinolinecarboxylic acid, 5-amino-1,4-dihydro-7-(3-amino-1-piperidinyl)-1-cyclopropyl-6,8-difluoro-4-oxo-
EINECS	Contact for details

Quality Control

Our 5-Amino-7-(3-Amino-1-Piperidyl)-1-Cyclopropyl-6,8-Difluoro-4-Oxo-Quino Line-3-Carboxylic Acid is manufactured under strict quality systems suitable for pharmaceutical applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.