Description

Intermedin B CAS NO 127214-87-3 is a bioactive peptide compound of significant interest in advanced biochemical research and development. This compound serves as a critical intermediate or reference standard in the synthesis and study of melanocortin receptor ligands and related peptide hormones. It is primarily utilized by pharmaceutical R&D teams, biotechnology firms, and academic research institutions focused on endocrinology, metabolic disorders, and novel therapeutic discovery.

Application

• Pharmaceutical Research & Development: As a key intermediate in the synthesis of melanocortin receptor (MCR) agonists and antagonists for potential drug candidates.
• Biochemical Reference Standard: Used for analytical method development, validation, and quality control in peptide analysis.
• Endocrinology Studies: A tool compound for investigating the physiological roles and signaling pathways of melanocyte-stimulating hormones (MSH) and adrenocorticotropic hormone (ACTH) derivatives.
• Metabolic Disorder Research: Applied in preclinical studies targeting obesity, diabetes, and inflammation due to its relevance to melanocortin pathways.
• Peptide Chemistry: Serves as a building block or precursor for the solid-phase or solution-phase synthesis of more complex peptide analogs.
• Academic & Contract Research: Supplied to universities and CROs for fundamental research and custom synthesis projects.

Basic Information

Product Name	Intermedin B
CAS No.	127214-87-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Intermedin B; Melanocyte-Stimulating Hormone Release-Inhibiting Factor (Fragment); MIF-1 related peptide; Tyr-Pro-Leu-Gly-NH2 (TPLG-NH2); PLG amide derivative; MSH release-inhibiting factor fragment; Tetrapeptide amide TPLG.
EINECS	Contact for details

Quality Control

Every batch of Intermedin B is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive (store away from light); therefore, containers must be kept tightly sealed in a desiccated environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.