Description

n-Acetyl-4-Deoxy-4-Acetamidoneuraminic Acid is a chemically modified derivative of sialic acid, a critical carbohydrate moiety in glycobiology. This compound serves as a valuable intermediate and reference standard in the research and development of glycoconjugates, sialidase inhibitors, and novel therapeutics. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors. Its defined structure is essential for studying carbohydrate-protein interactions and developing targeted biological agents.

Application

• Glycobiology Research: A key intermediate for synthesizing complex oligosaccharides and glycoconjugates to study cell signaling and recognition processes.
• Pharmaceutical Development: Used in the research of sialidase (neuraminidase) inhibitors for potential antiviral and antibacterial applications.
• Diagnostic Reagent Synthesis: Serves as a precursor for manufacturing high-specificity diagnostic probes and assay components targeting sialic acid-binding proteins.
• Bioconjugation & Labeling: Acts as a chemical handle for site-specific modification of proteins, antibodies, and other biomolecules.
• Enzyme Substrate & Inhibitor Studies: Employed as a substrate or inhibitor in enzymatic assays to characterize sialyltransferases and neuraminidases.
• Reference Standard: Provides a high-purity standard for analytical methods (HPLC, MS, NMR) in quality control and metabolic pathway analysis.

Basic Information

Product Name	n-Acetyl-4-Deoxy-4-Acetamidoneuraminic Acid
CAS No.	127099-59-6
Molecular Formula	C13H22N2O9
Molecular Weight	350.33 g/mol
Synonyms	4-Deoxy-4-acetamido-N-acetylneuraminic acid; 4-Deoxy-4-acetamido-D-neuraminic acid, N-acetyl-; 4-Acetamido-4-deoxy-N-acetylneuraminic acid; 4-Deoxy-4-acetamido-5-acetamidoneuraminic acid; N-Acetyl-4-acetamido-4-deoxyneuraminic acid; 4-Acetamido-4-deoxy-D-neuraminic acid, N-acetyl-; Sialic acid derivative, 4-deoxy-4-acetamido-N-acetyl-
EINECS	Contact for details

Quality Control

Our n-Acetyl-4-Deoxy-4-Acetamidoneuraminic Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.